秦洪强博士，中科院大连化物所研究员，博士生导师，国家自然科学基金委优秀青年基金获得者（2022）、中科院青年创新促进会优秀会员（2022）、国家重点研发计划项目课题负责人 （生物前沿技术专项，2022）。2013年博士毕业，并通过大连化物所优秀青年人才破格选拔项目，直聘为副研究员，2018年晋升为研究员。申请人长期致力于翻译后修饰蛋白质组分析新方法开发及其在肝癌等恶性肿瘤诊断中的应用研究，在Nat. Commun., Angew. Chem. Int. Ed., J. Am. Chem. Soc., Anal. Chem.等国际知名刊物共发表论文80余篇，论文总引用率超过2400次（截至2023.01.10）。
代表性论著：
(1) Li, J.; Zhou, J.; Tian, K.; Zhu, H.; Chen, Y.; Huang, Y.; Wang, G.; Gong, Z.; Qin, H.*; Ye, M.*, et al., ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J. Am. Chem. Soc., 2023, 145, 5252-5260.
(2) Fang, Z. #; Qin, H.#; Mao, J.; Wang, Z.; Zhang, N.; Wang, Y.; Liu, L.; Nie, Y.; Dong, M.; Ye, M., Glyco-Decipher enables glycan database-independent peptide matching and in-depth characterization of site-specific N-glycosylation. Nat. Commun. 2022, 13. DOI10.1038/s41467-022-29530-y.
(3) Chen, Y#.; Tang,F.#; Qin, H.#, *; Yue, X.; Nie, Y.; Huang, W.*; Ye, M*., Endo-M Mediated Chemoenzymatic Approach Enables Reversible Glycopeptide Labeling for O-GlcNAcylation Analysis. Angew. Chem. Int. Edit., 2022, 61. 0-10.1002/anie.202117849.
(4) Ji, Y.; Sun, L.; Chen, Y.; Qin, H.*; Xuan, W.*, Sirtuin-Derived Covalent Binder for the Selective Recognition of Protein Crotonylation. Angew. Chem. Int. Edit., 2022, 61. 10.1002/anie.202205522.
(5) Yue, X.#; Qin, H.#, *; Chen, Y.; Fang, Z.; Liu, L.; Zhu, H.; Liu, X.; Zhou, J.; Tian, K.; Qiao, X. *, Ye, M.*, Highly Efficient Enrichment of O-GalNAc Glycopeptides by Using Immobilized Metal Ion Affinity Chromatography. Anal. Chem. 2021, 93, 7579-7587.
(6) Chen, Y.; Qin, H.*; Yue, X.; Zhou, J.; Liu, L.; Nie, Y.; Ye, M.*, Highly Efficient Enrichment of O-GlcNAc Glycopeptides Based on Chemical Oxidation and Reversible Hydrazide Chemistry. Anal. Chem. 2021, 93, 16618-16627.
(7) Qin, H.; Dong, X.; Mao, J.; Chen, Y.; Dong, M.; Wang, L.; Guo, Z.; Liang, X.; Ye, M., Highly Efficient Analysis of Glycoprotein Sialylation in Human Serum by Simultaneous Quantification of Glycosites and Site-Specific Glycoforms. J. Proteome Res. 2019, 18, 3439-3446.
(8) Qin, H.; Cheng, K.; Zhu, J.; Mao, J.; Wang, F.; Dong, M.; Chen, R.; Guo, Z.; Liang, X.; Ye, M., et al., Proteomics Analysis of O-GaINAc Glycosylation in Human Serum by an Integrated Strategy. Anal. Chem. 2017, 89, 1469-1476.
(9) Dong, X.; Qin, H.; Mao, J.; Yu, D.; Li, X.; Shen, A.; Yan, J.; Yu, L.; Guo, Z.; Ye, M., et al., In-Depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge. Anal. Chem. 2017, 89, 3966-3972.
(10) Qin, H.; Hu, Z.; Wang, F.; Zhang, Y.; Zhao, L.; Xu, G.; Wu, R.; Zou, H., Facile preparation of ordered mesoporous silica-carbon composite nanoparticles for glycan enrichment. Chem. Commun. 2013, 49, 5162-5164.
(11) Qin, H.; Wang, F.; Zhang, Y.; Hu, Z.; Song, C.; Wu, R.; Ye, M.; Zou, H., Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation. Chem. Commun. 2012, 48, 6265-6267.
(12) Qin, H.; Wang, F.; Wang, P.; Zhao, L.; Zhu, J.; Yang, Q.; Wu, R. a.; Ye, M.; Zou, H., Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides. Chem. Commun. 2012, 48, 961-963.
(13) Qin, H.; Zhao, L.; Li, R.; Wu, R. a.; Zou, H., Size-Selective Enrichment of N-Linked Glycans Using Highly Ordered Mesoporous Carbon Material and Detection by MALDI-TOF MS. Anal. Chem. 2011, 83, 7721-7728.
(14) Qin, H.; Gao, P.; Wang, F.; Zhao, L.; Zhu, J.; Wang, A.; Zhang, T.; Wu, R. a.; Zou, H., Highly Efficient Extraction of Serum Peptides by Ordered Mesoporous Carbon. Angew. Chem. Int. Edit., 2011, 50, 12218-12221.
